Which Drugs Are Classified As Hazardous Drugs?

Which medications are classified as hazardous drugs?

Antineoplastic cytotoxic medications, anesthetic agents, anti-viral agents, and others, have been identified as hazardous.

These hazardous medications are capable of causing serious effects including cancer, organ toxicity, fertility problems, genetic damage, and birth defects..

What is considered a hazardous drug?

In pharmacology, hazardous drugs are drugs that are known to cause harm, which may or may not include genotoxicity (the ability to cause a change or mutation in genetic material).

Which drugs are cytotoxic?

Anthracyclines and other cytotoxic antibiotics. Drugs in this group are widely used. … Vinca alkaloids. The vinca alkaloids, vinblastine sulfate, vincristine sulfate, and vindesine sulfate, are used to treat a variety of cancers including leukaemias, lymphomas, and some solid tumours. … Antimetabolites. … Alkylating drugs.

Is medication a hazardous substance?

Cytotoxic drugs are hazardous substances, as defined by the Control of Substances Hazardous to Health Regulations 2002 (COSHH). … Pregnant workers are especially at risk, as some drugs may be harmful to the unborn child.

Is testosterone a hazardous drug?

May be harmful by inhalation, ingestion, or skin absorption. May cause cancer. May cause eye, skin, or respiratory system irritation.

What cancers does methotrexate treat?

Methotrexate is also used to treat certain types of cancer including cancers that begin in the tissues that form around a fertilized egg in the uterus, breast cancer, lung cancer, certain cancers of the head and neck, certain types of lymphoma, and leukemia (cancer that begins in the white blood cells).

What is the meaning of cytotoxic drugs?

Cytotoxic drugs or cytostatics (also cytotoxic chemotherapy) are drugs used to destroy cancer cells. Cytotoxic drugs inhibit cell division and in this way cause cancer cells to die. … The effects on normal cells are less pronounced and healthy cells also recover faster.

Is Methotrexate a hazardous drug?

Methotrexate is considered a Hazardous Drug as described in the NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings.

Why Lamivudine is called 3tc?

Lamivudine, sold under the brand name 3TC (Epivir in the US), is a type of antiretroviral (anti-HIV) drug called a nucleoside analogue or “nuke.” 3TC is used in combination with other antiretroviral drugs to treat (but not cure) HIV. 3TC is also found in these medicines: Kivexa – 3TC + abacavir.

What does lamivudine cure?

Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.

Why is Topamax a hazardous drug?

Material is irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation, ingestion, or skin absorption. May cause respiratory system irritation.

Is Methotrexate a steroid drug?

(1) Methotrexate is an effective steroid-sparing agent. (2) A dosage lower than the one recommended in the literature is effective. (3) Tolerance is good. (4) No benefit or detrimental effects in bone metabolism were observed after one year.

What does cytotoxic effect mean?

Cytotoxic refers to a substance or process which results in cell damage or cell death. The prefix “cyto” refers to cell and “toxic” to poison. The term is often used to describe chemotherapy drugs that kill cancer cells, but it may also be used to describe toxins, such as venom.

Is lamivudine hazardous?

CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. Ingestion may produce health damage*. Exposure may produce irreversible effects*.

Can you touch cytotoxic drugs?

Exposure may occur when preparing, administering, or transporting drugs, handling patient waste, transporting and disposing of waste, or cleaning spills. If at any time there is skin contact with any cytotoxic drug, the affected worker should thoroughly wash the affected area with soap and water.

What are the three types of hazardous drugs?

The format for the 2014 list was revised to include three groups of hazardous drugs: (1) Antineoplastic drugs; (2) Non-antineoplastic hazardous drugs; and (3) Drugs with reproductive effects.

What is the most common route of exposure to hazardous drugs?

The most common routes of exposure are skin contact with hazardous drug-contaminated workplace surfaces and inhalation of drug aerosols generated during compounding or administration of hazardous drugs.

Is Methotrexate a chemo drug?

Methotrexate is a chemotherapy drug used to treat many different cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Your doctor will talk to you about this treatment and its possible side effects before you agree (consent) to have treatment.